Cargando…

M1 macrophage-derived exosomes synergistically enhance the anti- bladder cancer effect of gemcitabine

Gemcitabine (GEM) is one of the first choice drugs for treating bladder cancer. In this study, we loaded M1 macrophage-derived exosomes (M1-Exo) with GEM by ultrasonication technique to derive an M1-Exo-GEM drug delivery system, and then explored its effects on bladder cancer. After inducing M1 pola...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Zhiling, Tang, Chenye, Sun, Chun, Ying, Xiangjun, Shen, Ruilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550252/ https://www.ncbi.nlm.nih.gov/pubmed/35929830 http://dx.doi.org/10.18632/aging.204200

Ejemplares similares

M1 Macrophage-Derived Exosomes Loaded with Gemcitabine and Deferasirox against Chemoresistant Pancreatic Cancer
por: Zhao, Yongmei, et al.
Publicado: (2021)

Short-term mortality risks among patients with non-metastatic bladder cancer
por: Zhai, Menghe, et al.
Publicado: (2020)

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients
por: Mey, V, et al.
Publicado: (2006)

Sunitinib Malate Synergistically Potentiates Anti-Tumor Effect of Gemcitabine in Human Bladder Cancer Cells
por: Yoon, Cheol Yong, et al.
Publicado: (2011)

Association between acute kidney injury and prognoses of cardiac surgery patients: Analysis of the MIMIC-III database
por: Sun, Chun, et al.
Publicado: (2023)

Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer
por: Tomko, Andrea M., et al.
Publicado: (2022)

LncRNA MAFG-AS1 regulates miR-125b-5p/SphK1 axis to promote the proliferation, migration, and invasion of bladder cancer cells
por: Tang, Chenye, et al.
Publicado: (2021)

Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization
por: Lu, Xiangjun, et al.
Publicado: (2023)

M2 Macrophage–Derived Exosomes Facilitate HCC Metastasis by Transferring α(M)β(2) Integrin to Tumor Cells
por: Wu, Jindao, et al.
Publicado: (2021)

Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression
por: Jiang, Ziming, et al.
Publicado: (2021)

Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction
por: Xu, Jianye, et al.
Publicado: (2021)

Targeting myeloid-derived suppressor cells with gemcitabine to enhance efficacy of adoptive cell therapy in bladder cancer
por: Bazargan, Sarah, et al.
Publicado: (2023)

Anticancer properties of cannabidiol and Δ(9)-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines
por: Whynot, Erin G., et al.
Publicado: (2023)

M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistance
por: Zheng, Naisheng, et al.
Publicado: (2023)

Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization
por: Pritchard, Alexandra, et al.
Publicado: (2020)

Edible Pueraria lobata-Derived Exosomes Promote M2 Macrophage Polarization
por: Wu, Jiaqi, et al.
Publicado: (2022)

Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy
por: Tang, Xiangjun, et al.
Publicado: (2022)

Exosome Treatment Enhances Anti-Inflammatory M2 Macrophages and Reduces Inflammation-Induced Pyroptosis in Doxorubicin-Induced Cardiomyopathy
por: Singla, Dinender K., et al.
Publicado: (2019)

Synergistic activity of troxacitabine (Troxatyl™) and gemcitabine in pancreatic cancer
por: Damaraju, Vijaya L, et al.
Publicado: (2007)

Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts
por: Vallo, Stefan, et al.
Publicado: (2016)

Exosomes Derived from Bone Marrow Stromal Cells (BMSCs) Enhance Tendon-Bone Healing by Regulating Macrophage Polarization
por: Shi, Youxing, et al.
Publicado: (2020)

Anti-tumor effect of AZD8055 against bladder cancer and bladder cancer-associated macrophages
por: Hu, Weimin, et al.
Publicado: (2023)

Exosomes Derived From M2b Macrophages Attenuate DSS-Induced Colitis
por: Yang, Ruibing, et al.
Publicado: (2019)

Exosomes Derived From M2 Macrophages Facilitate Osteogenesis and Reduce Adipogenesis of BMSCs
por: Li, Ziyi, et al.
Publicado: (2021)

Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing
por: Lyu, Leifeng, et al.
Publicado: (2022)

M2 macrophage-derived exosomes promote diabetic fracture healing by acting as an immunomodulator
por: Wang, Yili, et al.
Publicado: (2023)

Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA
por: Chen, Xutao, et al.
Publicado: (2022)

Biological Roles and Clinical Significance of Exosome-Derived Noncoding RNAs in Bladder Cancer
por: Tong, Yonghua, et al.
Publicado: (2021)

M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response
por: Du, Tong, et al.
Publicado: (2020)

Ellagic Acid Resensitizes Gemcitabine-Resistant Bladder Cancer Cells by Inhibiting Epithelial-Mesenchymal Transition and Gemcitabine Transporters
por: Wu, Ying-Si, et al.
Publicado: (2021)

Scorpion and centipede alleviates severe asthma through M2 macrophage-derived exosomal miR-30b-5p
por: Tang, Binqing, et al.
Publicado: (2022)

Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation
por: Wang, Piaopiao, et al.
Publicado: (2019)

Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines
por: Valdez, B C, et al.
Publicado: (2014)

MIR4435-2HG in exosomes promotes gastric carcinogenesis by inducing M2 polarization in macrophages
por: Li, Chaofeng, et al.
Publicado: (2022)

Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells
por: TAKEUCHI, HISASHI, et al.
Publicado: (2015)

PTH Derivative promotes wound healing via synergistic multicellular stimulating and exosomal activities
por: Shen, Yi-Fan, et al.
Publicado: (2020)

Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells
por: Bocci, G, et al.
Publicado: (2005)

Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer
por: Bulle, Ashenafi, et al.
Publicado: (2020)

KAT8/MOF-Mediated Anti-Cancer Mechanism of Gemcitabine in Human Bladder Cancer Cells
por: Zhu, Huihui, et al.
Publicado: (2021)

Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes
por: Heo, June Seok, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b08s0j36eo66t9o96u0ln3deur