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AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France

OBJECTIVES: Aortic root aneurysms often affect younger patients in whom valve-sparing surgery is challenging. Among current techniques, aortic valve-sparing root replacement described by Tirone David has shown encouraging results. The AORTLANTIC registry was instituted for a multicentre long-term ev...

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Autores principales: Dubost, Clément, Tomasi, Jacques, Ducroix, Antoine, Pluchon, Kevin, Escrig, Pierre, Fouquet, Olivier, Aupart, Arthur, Mirza, Alain, Fellah, Imen, Bezon, Eric, Baufreton, Christophe, El Arid, Jean Marc, Roussel, Jean-Christian, Verhoye, Jean-Philippe, Senage, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550271/
https://www.ncbi.nlm.nih.gov/pubmed/36173328
http://dx.doi.org/10.1093/icvts/ivac240
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author Dubost, Clément
Tomasi, Jacques
Ducroix, Antoine
Pluchon, Kevin
Escrig, Pierre
Fouquet, Olivier
Aupart, Arthur
Mirza, Alain
Fellah, Imen
Bezon, Eric
Baufreton, Christophe
El Arid, Jean Marc
Roussel, Jean-Christian
Verhoye, Jean-Philippe
Senage, Thomas
author_facet Dubost, Clément
Tomasi, Jacques
Ducroix, Antoine
Pluchon, Kevin
Escrig, Pierre
Fouquet, Olivier
Aupart, Arthur
Mirza, Alain
Fellah, Imen
Bezon, Eric
Baufreton, Christophe
El Arid, Jean Marc
Roussel, Jean-Christian
Verhoye, Jean-Philippe
Senage, Thomas
author_sort Dubost, Clément
collection PubMed
description OBJECTIVES: Aortic root aneurysms often affect younger patients in whom valve-sparing surgery is challenging. Among current techniques, aortic valve-sparing root replacement described by Tirone David has shown encouraging results. The AORTLANTIC registry was instituted for a multicentre long-term evaluation of this procedure. The current initial study evaluates the hospital outcomes of the procedure. METHODS: This is a retrospective study of patients operated between 1 January 2004 and 31 December 2020 in 6 hospitals in western France. All study data were recorded in the national digital database of the French Society of Cardiac Surgery: EPICARD. RESULTS: A total of 524 consecutive patients with a mean age of 53 (15.1) years underwent surgery. 13% (n = 68) of patients presented with acute aortic dissection, 16.5% (n = 86) had associated connective tissue pathology and 7.3% (n = 37) had bicuspid aortic valves. Preoperative aortic regurgitation (AR) ≥2/4 was present in 65.3% (n = 341) of patients. Aortic valvuloplasty was required in 18.6% (n = 95) of patients. At discharge, 92.8% (n = 461) of patients had no or 1/4 AR. The stroke rate was 1.9% (n = 10). Intra-hospital mortality was 1.9% (n = 10). CONCLUSIONS: The AORTLANTIC registry includes 6 centres in western France with >500 patients. Despite numerous complex cases (acute aortic dissections, bicuspid aortic valves, preoperative AR), aortic valve-sparing root replacement has a low intra-hospital mortality. The initial encouraging results of this multicentre study warrant further long-term evaluation by future studies.
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spelling pubmed-95502712022-10-11 AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France Dubost, Clément Tomasi, Jacques Ducroix, Antoine Pluchon, Kevin Escrig, Pierre Fouquet, Olivier Aupart, Arthur Mirza, Alain Fellah, Imen Bezon, Eric Baufreton, Christophe El Arid, Jean Marc Roussel, Jean-Christian Verhoye, Jean-Philippe Senage, Thomas Interact Cardiovasc Thorac Surg Vascular OBJECTIVES: Aortic root aneurysms often affect younger patients in whom valve-sparing surgery is challenging. Among current techniques, aortic valve-sparing root replacement described by Tirone David has shown encouraging results. The AORTLANTIC registry was instituted for a multicentre long-term evaluation of this procedure. The current initial study evaluates the hospital outcomes of the procedure. METHODS: This is a retrospective study of patients operated between 1 January 2004 and 31 December 2020 in 6 hospitals in western France. All study data were recorded in the national digital database of the French Society of Cardiac Surgery: EPICARD. RESULTS: A total of 524 consecutive patients with a mean age of 53 (15.1) years underwent surgery. 13% (n = 68) of patients presented with acute aortic dissection, 16.5% (n = 86) had associated connective tissue pathology and 7.3% (n = 37) had bicuspid aortic valves. Preoperative aortic regurgitation (AR) ≥2/4 was present in 65.3% (n = 341) of patients. Aortic valvuloplasty was required in 18.6% (n = 95) of patients. At discharge, 92.8% (n = 461) of patients had no or 1/4 AR. The stroke rate was 1.9% (n = 10). Intra-hospital mortality was 1.9% (n = 10). CONCLUSIONS: The AORTLANTIC registry includes 6 centres in western France with >500 patients. Despite numerous complex cases (acute aortic dissections, bicuspid aortic valves, preoperative AR), aortic valve-sparing root replacement has a low intra-hospital mortality. The initial encouraging results of this multicentre study warrant further long-term evaluation by future studies. Oxford University Press 2022-09-29 /pmc/articles/PMC9550271/ /pubmed/36173328 http://dx.doi.org/10.1093/icvts/ivac240 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Vascular
Dubost, Clément
Tomasi, Jacques
Ducroix, Antoine
Pluchon, Kevin
Escrig, Pierre
Fouquet, Olivier
Aupart, Arthur
Mirza, Alain
Fellah, Imen
Bezon, Eric
Baufreton, Christophe
El Arid, Jean Marc
Roussel, Jean-Christian
Verhoye, Jean-Philippe
Senage, Thomas
AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France
title AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France
title_full AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France
title_fullStr AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France
title_full_unstemmed AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France
title_short AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France
title_sort aortlantic: french registry of aortic valve-sparing root replacement, preliminary multicentre results from western france
topic Vascular
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550271/
https://www.ncbi.nlm.nih.gov/pubmed/36173328
http://dx.doi.org/10.1093/icvts/ivac240
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