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In-silico study of influence of HLA heterogeneity on CTL responses across ethnicities to SARS-CoV-2

Differences in outcome to COVID-19 infection in different individuals is largely attributed to genetic heterogeneity leading to differential immune responses across individuals and populations. HLA is one such genetic factor that varies across individuals leading to differences in how T-cell respons...

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Detalles Bibliográficos
Autores principales: Rao, Vishal, Chandra, Nagasuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550298/
https://www.ncbi.nlm.nih.gov/pubmed/36229378
http://dx.doi.org/10.1016/j.humimm.2022.09.008