Cargando…
Advances on genetic and genomic studies of ALV resistance
Avian leukosis (AL) is a general term for a variety of neoplastic diseases in avian caused by avian leukosis virus (ALV). No vaccine or drug is currently available for the disease. Therefore, the disease can result in severe economic losses in poultry flocks. Increasing the resistance of poultry to...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550310/ https://www.ncbi.nlm.nih.gov/pubmed/36217167 http://dx.doi.org/10.1186/s40104-022-00769-1 |
_version_ | 1784805854569037824 |
---|---|
author | Mo, Guodong Wei, Ping Hu, Bowen Nie, Qinghua Zhang, Xiquan |
author_facet | Mo, Guodong Wei, Ping Hu, Bowen Nie, Qinghua Zhang, Xiquan |
author_sort | Mo, Guodong |
collection | PubMed |
description | Avian leukosis (AL) is a general term for a variety of neoplastic diseases in avian caused by avian leukosis virus (ALV). No vaccine or drug is currently available for the disease. Therefore, the disease can result in severe economic losses in poultry flocks. Increasing the resistance of poultry to ALV may be one effective strategy. In this review, we provide an overview of the roles of genes associated with ALV infection in the poultry genome, including endogenous retroviruses, virus receptors, interferon-stimulated genes, and other immune-related genes. Furthermore, some methods and techniques that can improve ALV resistance in poultry are discussed. The objectives are willing to provide some valuable references for disease resistance breeding in poultry. |
format | Online Article Text |
id | pubmed-9550310 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-95503102022-10-11 Advances on genetic and genomic studies of ALV resistance Mo, Guodong Wei, Ping Hu, Bowen Nie, Qinghua Zhang, Xiquan J Anim Sci Biotechnol Review Avian leukosis (AL) is a general term for a variety of neoplastic diseases in avian caused by avian leukosis virus (ALV). No vaccine or drug is currently available for the disease. Therefore, the disease can result in severe economic losses in poultry flocks. Increasing the resistance of poultry to ALV may be one effective strategy. In this review, we provide an overview of the roles of genes associated with ALV infection in the poultry genome, including endogenous retroviruses, virus receptors, interferon-stimulated genes, and other immune-related genes. Furthermore, some methods and techniques that can improve ALV resistance in poultry are discussed. The objectives are willing to provide some valuable references for disease resistance breeding in poultry. BioMed Central 2022-10-11 /pmc/articles/PMC9550310/ /pubmed/36217167 http://dx.doi.org/10.1186/s40104-022-00769-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Mo, Guodong Wei, Ping Hu, Bowen Nie, Qinghua Zhang, Xiquan Advances on genetic and genomic studies of ALV resistance |
title | Advances on genetic and genomic studies of ALV resistance |
title_full | Advances on genetic and genomic studies of ALV resistance |
title_fullStr | Advances on genetic and genomic studies of ALV resistance |
title_full_unstemmed | Advances on genetic and genomic studies of ALV resistance |
title_short | Advances on genetic and genomic studies of ALV resistance |
title_sort | advances on genetic and genomic studies of alv resistance |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550310/ https://www.ncbi.nlm.nih.gov/pubmed/36217167 http://dx.doi.org/10.1186/s40104-022-00769-1 |
work_keys_str_mv | AT moguodong advancesongeneticandgenomicstudiesofalvresistance AT weiping advancesongeneticandgenomicstudiesofalvresistance AT hubowen advancesongeneticandgenomicstudiesofalvresistance AT nieqinghua advancesongeneticandgenomicstudiesofalvresistance AT zhangxiquan advancesongeneticandgenomicstudiesofalvresistance |