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Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

The United States Environmental Protection Agency (EPA) has been pursuing new high throughput in vitro assays to characterize endocrine disrupting chemicals (EDCs) that interact with estrogen receptor signaling. We characterize two new PRL-HeLa cell models expressing either inducible C-terminal (iGF...

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Detalles Bibliográficos
Autores principales:	Szafran, Adam T., Mancini, Maureen G., Stossi, Fabio, Mancini, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550643/ https://www.ncbi.nlm.nih.gov/pubmed/36238893 http://dx.doi.org/10.1016/j.isci.2022.105200

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