Cargando…
The global Protein-RNA interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function
The epithelial splicing regulatory proteins, ESRP1 and ESRP2, are essential for mammalian development through the regulation of a global program of alternative splicing of genes involved in the maintenance of epithelial cell function. To further inform our understanding of the molecular functions of...
Autores principales: | Peart, Natoya J., Hwang, Jae Yeon, Quesnel-Vallières, Mathieu, Sears, Matthew J., Yang, Yuequin, Stoilov, Peter, Barash, Yoseph, Park, Juw Won, Lynch, Kristen W., Carstens, Russ P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550651/ https://www.ncbi.nlm.nih.gov/pubmed/36238894 http://dx.doi.org/10.1016/j.isci.2022.105205 |
Ejemplares similares
-
Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
por: Lee, SungKyoung, et al.
Publicado: (2018) -
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
por: Bebee, Thomas W, et al.
Publicado: (2015) -
The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice
por: Peart, Natoya J., et al.
Publicado: (2022) -
Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number
por: Bebee, Thomas W., et al.
Publicado: (2016) -
Identifying common transcriptome signatures of cancer by interpreting deep learning models
por: Jha, Anupama, et al.
Publicado: (2022)