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Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study
Adverse drug reactions (ADRs) constitute a frequent cause of hospitalization in older people. The risk of ADRs is increased by the prescription of potentially inappropriate medications for older people (PIMs). The PRISCUS list and the FORTA classification represent established tools to detect PIMs....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Vienna
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550757/ https://www.ncbi.nlm.nih.gov/pubmed/36050603 http://dx.doi.org/10.1007/s00702-022-02541-1 |
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author | Schulze Westhoff, Martin Groh, Adrian Schröder, Sebastian Proskynitopoulos, Phileas Johannes Jahn, Kirsten Klietz, Martin Krichevsky, Benjamin Stichtenoth, Dirk O. Wedegärtner, Felix Bleich, Stefan Frieling, Helge Heck, Johannes |
author_facet | Schulze Westhoff, Martin Groh, Adrian Schröder, Sebastian Proskynitopoulos, Phileas Johannes Jahn, Kirsten Klietz, Martin Krichevsky, Benjamin Stichtenoth, Dirk O. Wedegärtner, Felix Bleich, Stefan Frieling, Helge Heck, Johannes |
author_sort | Schulze Westhoff, Martin |
collection | PubMed |
description | Adverse drug reactions (ADRs) constitute a frequent cause of hospitalization in older people. The risk of ADRs is increased by the prescription of potentially inappropriate medications for older people (PIMs). The PRISCUS list and the FORTA classification represent established tools to detect PIMs. The aim of the present study was to examine the prevalence and characteristics of PIM prescriptions on the gerontopsychiatric ward of a university hospital in Germany. To this aim, medication charts of 92 patients (mean age 75.9 ± 7.7 years; 66.3% female) were analyzed on a weekly basis until patient discharge by utilization of the PRISCUS list and the FORTA classification. Overall, 335 medication reviews comprising 2363 drug prescriptions were analyzed. 3.0% of the prescribed drugs were PIMs according to the PRISCUS list, with benzodiazepines and Z-drugs accounting for nearly half (49.3%) of all PIM prescriptions. 30.4% of the patients were prescribed at least one PRISCUS-PIM, while 43.5% of the study population took at least one FORTA class D drug. A considerable proportion of gerontopsychiatric patients were affected by PIMs; however, the overall number of PIM prescriptions in the study population was low. Further improvements in the quality of prescribing should target the use of sedating agents such as benzodiazepines and Z-drugs. Physicians should be aware of discrepancies between the PRISCUS list and the FORTA classification. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00702-022-02541-1. |
format | Online Article Text |
id | pubmed-9550757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-95507572022-10-12 Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study Schulze Westhoff, Martin Groh, Adrian Schröder, Sebastian Proskynitopoulos, Phileas Johannes Jahn, Kirsten Klietz, Martin Krichevsky, Benjamin Stichtenoth, Dirk O. Wedegärtner, Felix Bleich, Stefan Frieling, Helge Heck, Johannes J Neural Transm (Vienna) Psychiatry and Preclinical Psychiatric Studies - Original Article Adverse drug reactions (ADRs) constitute a frequent cause of hospitalization in older people. The risk of ADRs is increased by the prescription of potentially inappropriate medications for older people (PIMs). The PRISCUS list and the FORTA classification represent established tools to detect PIMs. The aim of the present study was to examine the prevalence and characteristics of PIM prescriptions on the gerontopsychiatric ward of a university hospital in Germany. To this aim, medication charts of 92 patients (mean age 75.9 ± 7.7 years; 66.3% female) were analyzed on a weekly basis until patient discharge by utilization of the PRISCUS list and the FORTA classification. Overall, 335 medication reviews comprising 2363 drug prescriptions were analyzed. 3.0% of the prescribed drugs were PIMs according to the PRISCUS list, with benzodiazepines and Z-drugs accounting for nearly half (49.3%) of all PIM prescriptions. 30.4% of the patients were prescribed at least one PRISCUS-PIM, while 43.5% of the study population took at least one FORTA class D drug. A considerable proportion of gerontopsychiatric patients were affected by PIMs; however, the overall number of PIM prescriptions in the study population was low. Further improvements in the quality of prescribing should target the use of sedating agents such as benzodiazepines and Z-drugs. Physicians should be aware of discrepancies between the PRISCUS list and the FORTA classification. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00702-022-02541-1. Springer Vienna 2022-09-02 2022 /pmc/articles/PMC9550757/ /pubmed/36050603 http://dx.doi.org/10.1007/s00702-022-02541-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Psychiatry and Preclinical Psychiatric Studies - Original Article Schulze Westhoff, Martin Groh, Adrian Schröder, Sebastian Proskynitopoulos, Phileas Johannes Jahn, Kirsten Klietz, Martin Krichevsky, Benjamin Stichtenoth, Dirk O. Wedegärtner, Felix Bleich, Stefan Frieling, Helge Heck, Johannes Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study |
title | Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study |
title_full | Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study |
title_fullStr | Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study |
title_full_unstemmed | Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study |
title_short | Potentially inappropriate medications according to PRISCUS list and FORTA (Fit fOR The Aged) classification in geriatric psychiatry: a cross-sectional study |
title_sort | potentially inappropriate medications according to priscus list and forta (fit for the aged) classification in geriatric psychiatry: a cross-sectional study |
topic | Psychiatry and Preclinical Psychiatric Studies - Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550757/ https://www.ncbi.nlm.nih.gov/pubmed/36050603 http://dx.doi.org/10.1007/s00702-022-02541-1 |
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