PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation

PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral inte...

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Detalles Bibliográficos
Autores principales: Murray, Julia, Cruickshank, Clare, Bird, Thomas, Bell, Philip, Braun, John, Chuter, Dave, Ferreira, Miguel Reis, Griffin, Clare, Hassan, Shama, Hujairi, Nabil, Melcher, Alan, Miles, Elizabeth, Naismith, Olivia, Panades, Miguel, Philipps, Lara, Reid, Alison, Rekowski, Jan, Sankey, Pete, Staffurth, John, Syndikus, Isabel, Tree, Alison, Wilkins, Anna, Hall, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550847/
https://www.ncbi.nlm.nih.gov/pubmed/36238579
http://dx.doi.org/10.1016/j.ctro.2022.09.003
Descripción
Sumario:PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral interspace) can improve outcomes for this patient group.

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