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PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation
PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral inte...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550847/ https://www.ncbi.nlm.nih.gov/pubmed/36238579 http://dx.doi.org/10.1016/j.ctro.2022.09.003 |
| _version_ | 1784805974012329984 |
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| author | Murray, Julia Cruickshank, Clare Bird, Thomas Bell, Philip Braun, John Chuter, Dave Ferreira, Miguel Reis Griffin, Clare Hassan, Shama Hujairi, Nabil Melcher, Alan Miles, Elizabeth Naismith, Olivia Panades, Miguel Philipps, Lara Reid, Alison Rekowski, Jan Sankey, Pete Staffurth, John Syndikus, Isabel Tree, Alison Wilkins, Anna Hall, Emma |
| author_facet | Murray, Julia Cruickshank, Clare Bird, Thomas Bell, Philip Braun, John Chuter, Dave Ferreira, Miguel Reis Griffin, Clare Hassan, Shama Hujairi, Nabil Melcher, Alan Miles, Elizabeth Naismith, Olivia Panades, Miguel Philipps, Lara Reid, Alison Rekowski, Jan Sankey, Pete Staffurth, John Syndikus, Isabel Tree, Alison Wilkins, Anna Hall, Emma |
| author_sort | Murray, Julia |
| collection | PubMed |
| description | PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral interspace) can improve outcomes for this patient group. |
| format | Online Article Text |
| id | pubmed-9550847 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-95508472022-10-12 PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation Murray, Julia Cruickshank, Clare Bird, Thomas Bell, Philip Braun, John Chuter, Dave Ferreira, Miguel Reis Griffin, Clare Hassan, Shama Hujairi, Nabil Melcher, Alan Miles, Elizabeth Naismith, Olivia Panades, Miguel Philipps, Lara Reid, Alison Rekowski, Jan Sankey, Pete Staffurth, John Syndikus, Isabel Tree, Alison Wilkins, Anna Hall, Emma Clin Transl Radiat Oncol Article PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral interspace) can improve outcomes for this patient group. Elsevier 2022-09-24 /pmc/articles/PMC9550847/ /pubmed/36238579 http://dx.doi.org/10.1016/j.ctro.2022.09.003 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Article Murray, Julia Cruickshank, Clare Bird, Thomas Bell, Philip Braun, John Chuter, Dave Ferreira, Miguel Reis Griffin, Clare Hassan, Shama Hujairi, Nabil Melcher, Alan Miles, Elizabeth Naismith, Olivia Panades, Miguel Philipps, Lara Reid, Alison Rekowski, Jan Sankey, Pete Staffurth, John Syndikus, Isabel Tree, Alison Wilkins, Anna Hall, Emma PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation |
| title | PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation |
| title_full | PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation |
| title_fullStr | PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation |
| title_full_unstemmed | PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation |
| title_short | PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation |
| title_sort | pearls – a multicentre phase ii/iii trial of extended field radiotherapy for androgen sensitive prostate cancer patients with psma‐avid pelvic and/or para-aortic lymph nodes at presentation |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550847/ https://www.ncbi.nlm.nih.gov/pubmed/36238579 http://dx.doi.org/10.1016/j.ctro.2022.09.003 |
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