Exogenous Indian hedgehog antagonist damages intervertebral discs homeostasis in adult mice

BACKGROUND: Vismodegib, as an exogenous Indian hedgehog (Ihh) antagonist, has been approved by the Food and Drug Administration (FDA) for the clinical treatment of patients with basal cell carcinoma, and previous observations implicate the potential therapeutic of vismodegib in osteoarthritis treatm...

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Detalles Bibliográficos
Autores principales: Chen, Ran, Tan, Ya, Li, Yang, Huang, Junlan, Kuang, Liang, Ni, Zhenhong, Lan, Haiyang, Long, Rui, Xie, Yangli, Chen, Hangang, Luo, Xiaoqing, Chen, Lin, Tang, Ying, Zhou, Siru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550854/
https://www.ncbi.nlm.nih.gov/pubmed/36263384
http://dx.doi.org/10.1016/j.jot.2022.09.009

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