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Deregulated hyaluronan metabolism in the tumor microenvironment drives cancer inflammation and tumor-associated immune suppression

Hyaluronan (HA) is known to be a prominent component of the extracellular matrix in tumors, and many solid cancers are characterized by aberrant HA metabolism resulting in increased production in tumor tissue. HA has been implicated in regulating a variety of cellular functions in tumor cells and tu...

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Detalles Bibliográficos
Autores principales: Donelan, William, Dominguez-Gutierrez, Paul R., Kusmartsev, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550864/
https://www.ncbi.nlm.nih.gov/pubmed/36238286
http://dx.doi.org/10.3389/fimmu.2022.971278

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