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Deregulated hyaluronan metabolism in the tumor microenvironment drives cancer inflammation and tumor-associated immune suppression
Hyaluronan (HA) is known to be a prominent component of the extracellular matrix in tumors, and many solid cancers are characterized by aberrant HA metabolism resulting in increased production in tumor tissue. HA has been implicated in regulating a variety of cellular functions in tumor cells and tu...
Autores principales: | Donelan, William, Dominguez-Gutierrez, Paul R., Kusmartsev, Sergei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550864/ https://www.ncbi.nlm.nih.gov/pubmed/36238286 http://dx.doi.org/10.3389/fimmu.2022.971278 |
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