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Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus

Haemonchus contortus is an important parasitic nematode of ruminants. Previous studies showed that H. contortus escape the immunity through complex mechanisms, including releasing excretory/secretory proteins (ESPs) to modulate the host immune response. However, the detailed mechanism through which...

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Detalles Bibliográficos
Autores principales: Wen, Zhaohai, Zhang, Yue, Feng, Jiajun, Aimulajiang, Kalibixiati, Aleem, Muhammad Tahir, Lu, Mingmin, Xu, Lixin, Song, Xiaokai, Li, Xiangrui, Yan, Ruofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551057/
https://www.ncbi.nlm.nih.gov/pubmed/36238295
http://dx.doi.org/10.3389/fimmu.2022.1013159