Spatial multiomic profiling reveals the novel polarization of foamy macrophages within necrotic granulomatous lesions developed in lungs of C3HeB/FeJ mice infected with Mycobacterium tuberculosis

Infection with Mycobacterium tuberculosis leads to the development of tuberculosis (TB) with the formation of granulomatous lesions. Foamy macrophages (FM) are a hallmark of TB granulomas, because they provide the primary platform of M. tuberculosis proliferation and the main source of caseous necro...

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Detalles Bibliográficos
Autores principales: Seto, Shintaro, Nakamura, Hajime, Guo, Tz-Chun, Hikichi, Haruka, Wakabayashi, Keiko, Miyabayashi, Akiko, Nagata, Toshi, Hijikata, Minako, Keicho, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551193/
https://www.ncbi.nlm.nih.gov/pubmed/36237431
http://dx.doi.org/10.3389/fcimb.2022.968543

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