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Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring
One new lignan sinensiol H (1) and two new bisnorlignans, sinensiols I and J (2 and 3), along with three known compounds were isolated from the whole plants of Selaginella sinensis. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as high-resolution mass spectromet...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Beilstein-Institut
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551277/ https://www.ncbi.nlm.nih.gov/pubmed/36262670 http://dx.doi.org/10.3762/bjoc.18.146 |
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author | Zhu, Qinfeng Gao, Beibei Chen, Qian Luo, Tiantian Xu, Guobo Liao, Shanggao |
author_facet | Zhu, Qinfeng Gao, Beibei Chen, Qian Luo, Tiantian Xu, Guobo Liao, Shanggao |
author_sort | Zhu, Qinfeng |
collection | PubMed |
description | One new lignan sinensiol H (1) and two new bisnorlignans, sinensiols I and J (2 and 3), along with three known compounds were isolated from the whole plants of Selaginella sinensis. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as high-resolution mass spectrometry. The absolute configuration of 1 was established by ECD calculation. Compounds 2 and 3 represent rare examples of naturally occurring 9,9'-bisnorlignans. All the isolated compounds were assayed for their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages. |
format | Online Article Text |
id | pubmed-9551277 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-95512772022-10-18 Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring Zhu, Qinfeng Gao, Beibei Chen, Qian Luo, Tiantian Xu, Guobo Liao, Shanggao Beilstein J Org Chem Full Research Paper One new lignan sinensiol H (1) and two new bisnorlignans, sinensiols I and J (2 and 3), along with three known compounds were isolated from the whole plants of Selaginella sinensis. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as high-resolution mass spectrometry. The absolute configuration of 1 was established by ECD calculation. Compounds 2 and 3 represent rare examples of naturally occurring 9,9'-bisnorlignans. All the isolated compounds were assayed for their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages. Beilstein-Institut 2022-10-07 /pmc/articles/PMC9551277/ /pubmed/36262670 http://dx.doi.org/10.3762/bjoc.18.146 Text en Copyright © 2022, Zhu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material. |
spellingShingle | Full Research Paper Zhu, Qinfeng Gao, Beibei Chen, Qian Luo, Tiantian Xu, Guobo Liao, Shanggao Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring |
title | Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring |
title_full | Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring |
title_fullStr | Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring |
title_full_unstemmed | Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring |
title_short | Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring |
title_sort | sinensiols h–j, three new lignan derivatives from selaginella sinensis (desv.) spring |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551277/ https://www.ncbi.nlm.nih.gov/pubmed/36262670 http://dx.doi.org/10.3762/bjoc.18.146 |
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