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Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium

Ubiquitin-specific peptidase 25 (USP25) is a key deubiquitylase belonging to the USP superfamily that is primarily involved in inflammation and the immune response. Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine that is regarded as the master switch that initiates and maintain...

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Detalles Bibliográficos
Autores principales: Chang, Wenchuan, Lv, Hao, Tan, Lu, Gao, Ziang, Liu, Peiqiang, Qin, Danxue, Zhang, Wei, Xu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551407/
https://www.ncbi.nlm.nih.gov/pubmed/36177892
http://dx.doi.org/10.3892/mmr.2022.12863