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Effects of Shu Bu Wenshen Guchang recipe on intestinal injury and the TLR4/NF-κB signaling pathways in mice with irinotecan-induced delayed-type diarrhea

BACKGROUND: Irinotecan (also known as CPT-11) is a topoisomerase I inhibitor that is primarily used for the treatment of advanced colorectal cancer. CPT-11 and its active metabolite SN-38 can directly damage intestinal mucosal cells. In addition, CPT-11 can activate the Toll-like receptor 4 (TLR4) i...

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Detalles Bibliográficos
Autores principales:	Zhang, Qiong, Jiang, Feilong, Tao, Jin, Wang, Huaibi, Sun, Mingling, He, Yancheng, Lai, Zonglang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552091/ https://www.ncbi.nlm.nih.gov/pubmed/36237235 http://dx.doi.org/10.21037/tcr-22-2145

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