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A triple-RBD-based mucosal vaccine provides broad protection against SARS-CoV-2 variants of concern

The rapid mutation and spread of SARS-CoV-2 variants urge the development of effective mucosal vaccines to provide broad-spectrum protection against the initial infection and thereby curb the transmission potential. Here, we designed a chimeric triple-RBD immunogen, 3Ro-NC, harboring one Delta RBD a...

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Detalles Bibliográficos
Autores principales:	Yang, Jingyi, Liu, Mei-Qin, Liu, Lin, Li, Xian, Xu, Mengxin, Lin, Haofeng, Liu, Shuning, Hu, Yunqi, Li, Bei, Liu, Bowen, Li, Min, Sun, Ying, Chen, Yao-Qing, Shi, Zheng-Li, Yan, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552159/ https://www.ncbi.nlm.nih.gov/pubmed/36220993 http://dx.doi.org/10.1038/s41423-022-00929-3

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