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Advanced lung adenocarcinoma (LUAD) patient with EGFR mutations benefited from multiline combination targeted therapies after osimertinib (AZD9291) resistance: a case report

BACKGROUND: The resistance mechanisms to osimertinib encompass on-target molecular alterations, such as the well-known epidermal growth factor receptor (EGFR) C797S resistance mutation, and off-target molecular alterations, such as the high-frequency MET amplification, but there’s no further clear-c...

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Detalles Bibliográficos
Autores principales:	Chen, Jingyu, Zhao, Xueqi, Wang, Jinlin, Liu, Fangfang, Zhang, Linli, Chen, Yuan, Chu, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552262/ https://www.ncbi.nlm.nih.gov/pubmed/36237272 http://dx.doi.org/10.21037/tcr-22-510

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