Association between CYP2D6 phenotype and recurrence of Plasmodium vivax infection in south Korean patients

BACKGROUND: Primaquine is activated by CYP2D6 in the hepatocytes. In Korea, primaquine is the only hypnozoitocidal agent used for patients with vivax malaria. Thus, patients with poor CYP2D6 activity could have an increased risk of primaquine failure and subsequent relapse. The study sought to ident...

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Detalles Bibliográficos
Autores principales: Choi, Sungim, Choi, Heun, Park, Seong Yeon, Kwak, Yee Gyung, Song, Je Eun, Shin, So Youn, Baek, Ji Hyeon, Shin, Hyun-IL, Cho, Shin-Hyung, Lee, Sang-Eun, Kwon, Jeong-Ran, Park, Sookkyung, Kim, Miyoung, Oh, Hong Sang, Kim, Yong Chan, Kim, Min Jae, Yeom, Joon-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552356/
https://www.ncbi.nlm.nih.gov/pubmed/36217154
http://dx.doi.org/10.1186/s12936-022-04311-6

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