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CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response
BACKGROUND: Soft tissue sarcomas (STS) are heterogeneous and pro-metastatic tumors. Identification of accurate prognostic factors and novel therapeutic targets are crucial. CSPG4 is a cell surface proteoglycan with oncogenic functions. It recently emerged as a potential target for immunotherapy, inc...
Autores principales: | Boudin, Laurys, de Nonneville, A, Finetti, Pascal, Mescam, Léna, Le Cesne, A, Italiano, Antoine, Blay, Jean-Yves, Birnbaum, Daniel, Mamessier, Emilie, Bertucci, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552405/ https://www.ncbi.nlm.nih.gov/pubmed/36221119 http://dx.doi.org/10.1186/s12967-022-03679-y |
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