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Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study
BACKGROUND: Gout is a highly hereditary disease, but not all those carrying well-known risk variants have developing gout attack even in hyperuricemia status. We performed a genome-wide association study (GWAS) and polygenic risk score (PRS) analysis to illustrate the new genetic architectures of go...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552457/ https://www.ncbi.nlm.nih.gov/pubmed/36221101 http://dx.doi.org/10.1186/s13075-022-02917-4 |