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Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases
We present a clinical case where a complex abnormal non‐invasive prenatal test (NIPT) result in a research project revealed carcinoma of the breast in the pregnant woman. Furthermore, the NIPT result did not demonstrate the same fetal chromosomal aberration as the chorion villus sample. A literature...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552546/ https://www.ncbi.nlm.nih.gov/pubmed/36245448 http://dx.doi.org/10.1002/ccr3.6280 |
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author | Moellgaard, Maria Hammer Lund, Ida Charlotte Bay Becher, Naja Skytte, Anne‐Bine Andreasen, Lotte Srebniak, Malgorzata Ilona Vogel, Ida |
author_facet | Moellgaard, Maria Hammer Lund, Ida Charlotte Bay Becher, Naja Skytte, Anne‐Bine Andreasen, Lotte Srebniak, Malgorzata Ilona Vogel, Ida |
author_sort | Moellgaard, Maria Hammer |
collection | PubMed |
description | We present a clinical case where a complex abnormal non‐invasive prenatal test (NIPT) result in a research project revealed carcinoma of the breast in the pregnant woman. Furthermore, the NIPT result did not demonstrate the same fetal chromosomal aberration as the chorion villus sample. A literature search for similar cases was performed identifying 43 unique cases, where abnormal NIPT results were related to maternal malignancy. Malignancy is a rare but important cause of complex abnormal non‐invasive prenatal test (NIPT) results and should be considered when fetal karyotype and abnormal NIPT results are discordant. Furthermore, a follow‐up invasive sample is essential for correct fetal diagnosis when abnormal NIPT results are found. |
format | Online Article Text |
id | pubmed-9552546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95525462022-10-14 Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases Moellgaard, Maria Hammer Lund, Ida Charlotte Bay Becher, Naja Skytte, Anne‐Bine Andreasen, Lotte Srebniak, Malgorzata Ilona Vogel, Ida Clin Case Rep Case Report We present a clinical case where a complex abnormal non‐invasive prenatal test (NIPT) result in a research project revealed carcinoma of the breast in the pregnant woman. Furthermore, the NIPT result did not demonstrate the same fetal chromosomal aberration as the chorion villus sample. A literature search for similar cases was performed identifying 43 unique cases, where abnormal NIPT results were related to maternal malignancy. Malignancy is a rare but important cause of complex abnormal non‐invasive prenatal test (NIPT) results and should be considered when fetal karyotype and abnormal NIPT results are discordant. Furthermore, a follow‐up invasive sample is essential for correct fetal diagnosis when abnormal NIPT results are found. John Wiley and Sons Inc. 2022-10-11 /pmc/articles/PMC9552546/ /pubmed/36245448 http://dx.doi.org/10.1002/ccr3.6280 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Moellgaard, Maria Hammer Lund, Ida Charlotte Bay Becher, Naja Skytte, Anne‐Bine Andreasen, Lotte Srebniak, Malgorzata Ilona Vogel, Ida Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
title | Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
title_full | Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
title_fullStr | Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
title_full_unstemmed | Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
title_short | Incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
title_sort | incidental finding of maternal malignancy in an unusual non‐invasive prenatal test and a review of similar cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552546/ https://www.ncbi.nlm.nih.gov/pubmed/36245448 http://dx.doi.org/10.1002/ccr3.6280 |
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