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Sequelae of Corrosive Injury in Children: An Observational Study

AIM: This study aims to determine the sequelae of corrosive ingestion in children. METHODS: A retrospective study was conducted in the Department of Pediatric Surgery at a Tertiary Center. The children presenting between January 2015 and December 2020 with a history of ingestion of caustic agents we...

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Autores principales: Radhakrishna, Veerabhadra, Kumar, Nitin, Gadgade, Bahubali Deepak, Vasudev, Raghunath Bangalore, Alladi, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552654/
https://www.ncbi.nlm.nih.gov/pubmed/36238332
http://dx.doi.org/10.4103/jiaps.jiaps_133_21
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author Radhakrishna, Veerabhadra
Kumar, Nitin
Gadgade, Bahubali Deepak
Vasudev, Raghunath Bangalore
Alladi, Anand
author_facet Radhakrishna, Veerabhadra
Kumar, Nitin
Gadgade, Bahubali Deepak
Vasudev, Raghunath Bangalore
Alladi, Anand
author_sort Radhakrishna, Veerabhadra
collection PubMed
description AIM: This study aims to determine the sequelae of corrosive ingestion in children. METHODS: A retrospective study was conducted in the Department of Pediatric Surgery at a Tertiary Center. The children presenting between January 2015 and December 2020 with a history of ingestion of caustic agents were included in the study. RESULTS: A total of 26 children were included in the study. The children with suicidal attempts were significantly older than those who ingested the corrosive agents accidentally (14.2 ± 1.9 years vs. 6 ± 3.3 years; P < 0.01; Student's t-test). Sixteen (62%) children had esophageal strictures, 8 (31%) had pyloric strictures, and a child (4%) had both esophageal and gastric strictures. Eight (31%) children required an initial feeding jejunostomy and 6 (23%) required a feeding gastrostomy as they had significant weight loss on presentation. Eleven (65%) esophageal strictures responded to the dilatation regimen and are symptom-free on follow-up. Three (18%) children with esophageal stricture underwent esophageal replacement. Eight (31%) children had a pyloric stricture and all of them were treated with a modified Billroth I gastro-duodenostomy. The children who presented after 2 months were found to have a significantly increased need for esophageal replacement (3/9 vs. 0/17; P = 0.03; Fischer's exact test). CONCLUSION: The corrosive ingestion in children is associated with higher morbidity. The sequelae include esophageal and antro-pyloric strictures. A feeding gastrostomy or jejunostomy was required in more than half of the patients. The children presenting after 2 months of ingestion were associated with an increased need for esophageal replacement.
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spelling pubmed-95526542022-10-12 Sequelae of Corrosive Injury in Children: An Observational Study Radhakrishna, Veerabhadra Kumar, Nitin Gadgade, Bahubali Deepak Vasudev, Raghunath Bangalore Alladi, Anand J Indian Assoc Pediatr Surg Original Article AIM: This study aims to determine the sequelae of corrosive ingestion in children. METHODS: A retrospective study was conducted in the Department of Pediatric Surgery at a Tertiary Center. The children presenting between January 2015 and December 2020 with a history of ingestion of caustic agents were included in the study. RESULTS: A total of 26 children were included in the study. The children with suicidal attempts were significantly older than those who ingested the corrosive agents accidentally (14.2 ± 1.9 years vs. 6 ± 3.3 years; P < 0.01; Student's t-test). Sixteen (62%) children had esophageal strictures, 8 (31%) had pyloric strictures, and a child (4%) had both esophageal and gastric strictures. Eight (31%) children required an initial feeding jejunostomy and 6 (23%) required a feeding gastrostomy as they had significant weight loss on presentation. Eleven (65%) esophageal strictures responded to the dilatation regimen and are symptom-free on follow-up. Three (18%) children with esophageal stricture underwent esophageal replacement. Eight (31%) children had a pyloric stricture and all of them were treated with a modified Billroth I gastro-duodenostomy. The children who presented after 2 months were found to have a significantly increased need for esophageal replacement (3/9 vs. 0/17; P = 0.03; Fischer's exact test). CONCLUSION: The corrosive ingestion in children is associated with higher morbidity. The sequelae include esophageal and antro-pyloric strictures. A feeding gastrostomy or jejunostomy was required in more than half of the patients. The children presenting after 2 months of ingestion were associated with an increased need for esophageal replacement. Wolters Kluwer - Medknow 2022 2022-07-26 /pmc/articles/PMC9552654/ /pubmed/36238332 http://dx.doi.org/10.4103/jiaps.jiaps_133_21 Text en Copyright: © 2022 Journal of Indian Association of Pediatric Surgeons https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Radhakrishna, Veerabhadra
Kumar, Nitin
Gadgade, Bahubali Deepak
Vasudev, Raghunath Bangalore
Alladi, Anand
Sequelae of Corrosive Injury in Children: An Observational Study
title Sequelae of Corrosive Injury in Children: An Observational Study
title_full Sequelae of Corrosive Injury in Children: An Observational Study
title_fullStr Sequelae of Corrosive Injury in Children: An Observational Study
title_full_unstemmed Sequelae of Corrosive Injury in Children: An Observational Study
title_short Sequelae of Corrosive Injury in Children: An Observational Study
title_sort sequelae of corrosive injury in children: an observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552654/
https://www.ncbi.nlm.nih.gov/pubmed/36238332
http://dx.doi.org/10.4103/jiaps.jiaps_133_21
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