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Research Advances in the Treatment of Allergic Rhinitis by Probiotics
Allergic rhinitis (AR) impairs the quality of life of patients and reduces the efficiency of social work, it is an increasingly serious public medical and economic problem in the world. Conventional anti-allergic drugs for the treatment of allergic rhinitis (AR) can cause certain side effects, which...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552798/ https://www.ncbi.nlm.nih.gov/pubmed/36238950 http://dx.doi.org/10.2147/JAA.S382978 |
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author | Liu, Peng Hu, Tianyong Kang, Chenglin Liu, Jiangqi Zhang, Jin Ran, Hong Zeng, Xianhai Qiu, Shuqi |
author_facet | Liu, Peng Hu, Tianyong Kang, Chenglin Liu, Jiangqi Zhang, Jin Ran, Hong Zeng, Xianhai Qiu, Shuqi |
author_sort | Liu, Peng |
collection | PubMed |
description | Allergic rhinitis (AR) impairs the quality of life of patients and reduces the efficiency of social work, it is an increasingly serious public medical and economic problem in the world. Conventional anti-allergic drugs for the treatment of allergic rhinitis (AR) can cause certain side effects, which limit the quality of life of patients. Therefore, it makes sense to look for other forms of treatment. Several studies in recent years have shown that probiotics have shown anti-allergic effects in various mouse and human studies. For example, the application of certain probiotic strains can effectively relieve the typical nasal and ocular symptoms of allergic rhinitis in children and adults, thereby improving the quality of life and work efficiency. At the same time, previous studies in humans and mice have found that probiotics can produce multiple effects, such as reduction of Th2 cell inflammatory factors and/or increase of Th1 cell inflammatory factors, changes in allergy-related immunoglobulins and cell migration, regulate Th1/Th2 balance or restore intestinal microbiota disturbance. For patients with limited activity or allergic rhinitis with more attacks and longer attack duration, oral probiotics have positive effects. The efficacy of probiotics in the prevention and treatment of allergic rhinitis is remarkable, but its specific mechanism needs further study. This review summarizes the research progress of probiotics in the treatment of allergic rhinitis in recent years. |
format | Online Article Text |
id | pubmed-9552798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-95527982022-10-12 Research Advances in the Treatment of Allergic Rhinitis by Probiotics Liu, Peng Hu, Tianyong Kang, Chenglin Liu, Jiangqi Zhang, Jin Ran, Hong Zeng, Xianhai Qiu, Shuqi J Asthma Allergy Review Allergic rhinitis (AR) impairs the quality of life of patients and reduces the efficiency of social work, it is an increasingly serious public medical and economic problem in the world. Conventional anti-allergic drugs for the treatment of allergic rhinitis (AR) can cause certain side effects, which limit the quality of life of patients. Therefore, it makes sense to look for other forms of treatment. Several studies in recent years have shown that probiotics have shown anti-allergic effects in various mouse and human studies. For example, the application of certain probiotic strains can effectively relieve the typical nasal and ocular symptoms of allergic rhinitis in children and adults, thereby improving the quality of life and work efficiency. At the same time, previous studies in humans and mice have found that probiotics can produce multiple effects, such as reduction of Th2 cell inflammatory factors and/or increase of Th1 cell inflammatory factors, changes in allergy-related immunoglobulins and cell migration, regulate Th1/Th2 balance or restore intestinal microbiota disturbance. For patients with limited activity or allergic rhinitis with more attacks and longer attack duration, oral probiotics have positive effects. The efficacy of probiotics in the prevention and treatment of allergic rhinitis is remarkable, but its specific mechanism needs further study. This review summarizes the research progress of probiotics in the treatment of allergic rhinitis in recent years. Dove 2022-10-07 /pmc/articles/PMC9552798/ /pubmed/36238950 http://dx.doi.org/10.2147/JAA.S382978 Text en © 2022 Liu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Liu, Peng Hu, Tianyong Kang, Chenglin Liu, Jiangqi Zhang, Jin Ran, Hong Zeng, Xianhai Qiu, Shuqi Research Advances in the Treatment of Allergic Rhinitis by Probiotics |
title | Research Advances in the Treatment of Allergic Rhinitis by Probiotics |
title_full | Research Advances in the Treatment of Allergic Rhinitis by Probiotics |
title_fullStr | Research Advances in the Treatment of Allergic Rhinitis by Probiotics |
title_full_unstemmed | Research Advances in the Treatment of Allergic Rhinitis by Probiotics |
title_short | Research Advances in the Treatment of Allergic Rhinitis by Probiotics |
title_sort | research advances in the treatment of allergic rhinitis by probiotics |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552798/ https://www.ncbi.nlm.nih.gov/pubmed/36238950 http://dx.doi.org/10.2147/JAA.S382978 |
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