Phosphorylated CRMP1, axon guidance protein, is a component of spheroids and is involved in axonal pathology in amyotrophic lateral sclerosis

In amyotrophic lateral sclerosis (ALS), neurodegeneration is characterized by distal axonopathy that begins at the distal axons, including the neuromuscular junctions, and progresses proximally in a “dying back” manner prior to the degeneration of cell bodies. However, the molecular mechanism for di...

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Detalles Bibliográficos
Autores principales: Kawamoto, Yuko, Tada, Mikiko, Asano, Tetsuya, Nakamura, Haruko, Jitsuki-Takahashi, Aoi, Makihara, Hiroko, Kubota, Shun, Hashiguchi, Shunta, Kunii, Misako, Ohshima, Toshio, Goshima, Yoshio, Takeuchi, Hideyuki, Doi, Hiroshi, Nakamura, Fumio, Tanaka, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552802/
https://www.ncbi.nlm.nih.gov/pubmed/36237616
http://dx.doi.org/10.3389/fneur.2022.994676

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