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COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment

Although periconception vaccination is important to maternal and neonatal health, little is known about the COVID-19 vaccine hesitancy among infertile couples seeking fertility treatment. Thus, we conducted this survey among infertile patients in a reproductive medicine center, between September 202...

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Autores principales: Wang, Xinyan, Wang, Huiyan, Du, Aijun, Wang, Junchao, Shi, Jie, Zhang, Yunshan, Zhang, Yinfeng, Ma, Junfang, Meng, Wenjia, Lv, Jiabei, Luo, Haining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552881/
https://www.ncbi.nlm.nih.gov/pubmed/36238271
http://dx.doi.org/10.3389/fimmu.2022.973600
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author Wang, Xinyan
Wang, Huiyan
Du, Aijun
Wang, Junchao
Shi, Jie
Zhang, Yunshan
Zhang, Yinfeng
Ma, Junfang
Meng, Wenjia
Lv, Jiabei
Luo, Haining
author_facet Wang, Xinyan
Wang, Huiyan
Du, Aijun
Wang, Junchao
Shi, Jie
Zhang, Yunshan
Zhang, Yinfeng
Ma, Junfang
Meng, Wenjia
Lv, Jiabei
Luo, Haining
author_sort Wang, Xinyan
collection PubMed
description Although periconception vaccination is important to maternal and neonatal health, little is known about the COVID-19 vaccine hesitancy among infertile couples seeking fertility treatment. Thus, we conducted this survey among infertile patients in a reproductive medicine center, between September 2021 and December 2021, to estimate the prevalence of COVID-19 vaccine hesitancy and its influencing factors. Information was collected through face-to-face interviews among volunteers. Among the 987 included interviewees, 17.33% reported hesitancy in primary vaccination, 25.63% reported hesitancy in booster vaccination, and 32.32% delayed the primary vaccination. Hesitancy in primary vaccination was associated with unexplained infertility (OR: 1.77, 95% CI: 1.05-2.98), ongoing IVF treatment (OR: 2.17, 95% CI: 1.22-3.89), concerns for vaccine safety (OR: 4.13, 95% CI: 2.66-6.42), effectiveness (OR: 1.62, 95% CI: 1.15-2.28), and influence on pregnancy (OR: 2.80, 95% CI: 1.68-4.67). These factors were also associated with hesitancy in booster vaccination. Delay of the primary vaccination was inversely associated with a college or above degree (OR: 0.49, 95% CI: 0.27-0.87), previous history of influenza vaccination (OR: 0.67, 95% CI: 0.46-0.98), and was positively associated with concerns for the influence on pregnancy (OR: 7.78, 95% CI: 5.01-12.07). It is necessary to carry out targeted education program by health professionals to publicize the benefits of periconception vaccination, and to reduce the resistance to COVID-19 vaccine among infertile couples.
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spelling pubmed-95528812022-10-12 COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment Wang, Xinyan Wang, Huiyan Du, Aijun Wang, Junchao Shi, Jie Zhang, Yunshan Zhang, Yinfeng Ma, Junfang Meng, Wenjia Lv, Jiabei Luo, Haining Front Immunol Immunology Although periconception vaccination is important to maternal and neonatal health, little is known about the COVID-19 vaccine hesitancy among infertile couples seeking fertility treatment. Thus, we conducted this survey among infertile patients in a reproductive medicine center, between September 2021 and December 2021, to estimate the prevalence of COVID-19 vaccine hesitancy and its influencing factors. Information was collected through face-to-face interviews among volunteers. Among the 987 included interviewees, 17.33% reported hesitancy in primary vaccination, 25.63% reported hesitancy in booster vaccination, and 32.32% delayed the primary vaccination. Hesitancy in primary vaccination was associated with unexplained infertility (OR: 1.77, 95% CI: 1.05-2.98), ongoing IVF treatment (OR: 2.17, 95% CI: 1.22-3.89), concerns for vaccine safety (OR: 4.13, 95% CI: 2.66-6.42), effectiveness (OR: 1.62, 95% CI: 1.15-2.28), and influence on pregnancy (OR: 2.80, 95% CI: 1.68-4.67). These factors were also associated with hesitancy in booster vaccination. Delay of the primary vaccination was inversely associated with a college or above degree (OR: 0.49, 95% CI: 0.27-0.87), previous history of influenza vaccination (OR: 0.67, 95% CI: 0.46-0.98), and was positively associated with concerns for the influence on pregnancy (OR: 7.78, 95% CI: 5.01-12.07). It is necessary to carry out targeted education program by health professionals to publicize the benefits of periconception vaccination, and to reduce the resistance to COVID-19 vaccine among infertile couples. Frontiers Media S.A. 2022-09-27 /pmc/articles/PMC9552881/ /pubmed/36238271 http://dx.doi.org/10.3389/fimmu.2022.973600 Text en Copyright © 2022 Wang, Wang, Du, Wang, Shi, Zhang, Zhang, Ma, Meng, Lv and Luo https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Wang, Xinyan
Wang, Huiyan
Du, Aijun
Wang, Junchao
Shi, Jie
Zhang, Yunshan
Zhang, Yinfeng
Ma, Junfang
Meng, Wenjia
Lv, Jiabei
Luo, Haining
COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
title COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
title_full COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
title_fullStr COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
title_full_unstemmed COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
title_short COVID-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
title_sort covid-19 vaccine hesitancy and associated factors among infertile couples undergoing assisted reproductive treatment
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552881/
https://www.ncbi.nlm.nih.gov/pubmed/36238271
http://dx.doi.org/10.3389/fimmu.2022.973600
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