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Placebo Response to Oral Administration in Osteoarthritis Clinical Trials and Its Associated Factors: A Model-Based Meta-analysis

IMPORTANCE: In osteoarthritis (OA) clinical trials, a placebo is often used as control. Therefore, a thorough understanding of the placebo response is important for guiding drug development in OA. OBJECTIVE: To develop an oral placebo response model for OA. DATA SOURCES: PubMed, EMBASE, and Cochrane...

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Detalles Bibliográficos
Autores principales: Wen, Xin, Luo, Jieren, Mai, Yiying, Li, Yang, Cao, Ying, Li, Zewei, Han, Shun, Fu, Quanyi, Zheng, Qingshan, Ding, Changhai, Zhu, Zhaohua, Li, Lujin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552894/
https://www.ncbi.nlm.nih.gov/pubmed/36215072
http://dx.doi.org/10.1001/jamanetworkopen.2022.35060