Neat1 promotes acute kidney injury to chronic kidney disease by facilitating tubular epithelial cells apoptosis via sequestering miR-129-5p

Acute kidney injury (AKI) is increasingly identified as a crucial risk factor for progression to CKD. However, the factors governing AKI to CKD progression remain largely unknown. By high-throughput RNA sequencing, we found that Neat1_2, a transcript variant of Neat1, was upregulated in 40-min ische...

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Detalles Bibliográficos
Autores principales: Ma, Tongtong, Li, Hongwei, Liu, Hui, Peng, Yili, Lin, Tong, Deng, Zhiya, Jia, Nan, Chen, Zhongqing, Wang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552914/
https://www.ncbi.nlm.nih.gov/pubmed/35619557
http://dx.doi.org/10.1016/j.ymthe.2022.05.019

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