Cargando…
Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents
One of the main objectives when assessing patients who react to antineoplastics must be to ensure that they receive the required treatments without delay. From January to July 2021, at the Allergy Department at the Provincial University Consortium Hospital a pilot study was performed in which those...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552947/ https://www.ncbi.nlm.nih.gov/pubmed/36238927 http://dx.doi.org/10.3389/falgy.2022.868300 |
_version_ | 1784806360128421888 |
---|---|
author | Borrás Cuartero, Julián Farzanegan Miñano, Roxana Torres Gorriz, María Cruz Germán Sánchez, Adrián Aznar, Raquel Cervera Raducan, Isabela Castelló Carrascosa, Jose Vicente Sanchez Hernandez, Alfredo Enrique, Ernesto |
author_facet | Borrás Cuartero, Julián Farzanegan Miñano, Roxana Torres Gorriz, María Cruz Germán Sánchez, Adrián Aznar, Raquel Cervera Raducan, Isabela Castelló Carrascosa, Jose Vicente Sanchez Hernandez, Alfredo Enrique, Ernesto |
author_sort | Borrás Cuartero, Julián |
collection | PubMed |
description | One of the main objectives when assessing patients who react to antineoplastics must be to ensure that they receive the required treatments without delay. From January to July 2021, at the Allergy Department at the Provincial University Consortium Hospital a pilot study was performed in which those patients suspected of having suffered a type I hypersensitivity reaction (grade 1 or 2) following Brown's anaphylaxis severity grading to a platin agent at the Provincial University Consortium oncology day unit, and once the reaction was properly treated and completely resolved, were subjected to a new procedure named as Same-Day Desensitization, which consists in the reintroduction and administration of full chemotherapy dose by allergists on the same day of the reaction by following the 1 bag/10 step protocol, looking forwards to systematize same-day reexposure using Same-Day Desensitization, doing it in the safest way possible. In total, 9 oncological patients suspected of having suffered a type I hypersensitivity reaction (grade 1 or 2) to a platin agent received total dose administration the same day of the initial reaction by following Same-Day Desensitization 1 bag/10 step protocol, without presenting further reactions. The manuscript describes a new approach in the use of Rapid Drug Desensitizations in reactive oncologic patients in treatment with platin agents, presenting the first 9 cases of oncologic patients who have been submitted to this procedure. |
format | Online Article Text |
id | pubmed-9552947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95529472022-10-12 Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents Borrás Cuartero, Julián Farzanegan Miñano, Roxana Torres Gorriz, María Cruz Germán Sánchez, Adrián Aznar, Raquel Cervera Raducan, Isabela Castelló Carrascosa, Jose Vicente Sanchez Hernandez, Alfredo Enrique, Ernesto Front Allergy Allergy One of the main objectives when assessing patients who react to antineoplastics must be to ensure that they receive the required treatments without delay. From January to July 2021, at the Allergy Department at the Provincial University Consortium Hospital a pilot study was performed in which those patients suspected of having suffered a type I hypersensitivity reaction (grade 1 or 2) following Brown's anaphylaxis severity grading to a platin agent at the Provincial University Consortium oncology day unit, and once the reaction was properly treated and completely resolved, were subjected to a new procedure named as Same-Day Desensitization, which consists in the reintroduction and administration of full chemotherapy dose by allergists on the same day of the reaction by following the 1 bag/10 step protocol, looking forwards to systematize same-day reexposure using Same-Day Desensitization, doing it in the safest way possible. In total, 9 oncological patients suspected of having suffered a type I hypersensitivity reaction (grade 1 or 2) to a platin agent received total dose administration the same day of the initial reaction by following Same-Day Desensitization 1 bag/10 step protocol, without presenting further reactions. The manuscript describes a new approach in the use of Rapid Drug Desensitizations in reactive oncologic patients in treatment with platin agents, presenting the first 9 cases of oncologic patients who have been submitted to this procedure. Frontiers Media S.A. 2022-06-16 /pmc/articles/PMC9552947/ /pubmed/36238927 http://dx.doi.org/10.3389/falgy.2022.868300 Text en Copyright © 2022 Borrás Cuartero, Farzanegan Miñano, Torres Gorriz, Germán Sánchez, Aznar, Raducan, Castelló Carrascosa, Sanchez Hernandez and Enrique. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Allergy Borrás Cuartero, Julián Farzanegan Miñano, Roxana Torres Gorriz, María Cruz Germán Sánchez, Adrián Aznar, Raquel Cervera Raducan, Isabela Castelló Carrascosa, Jose Vicente Sanchez Hernandez, Alfredo Enrique, Ernesto Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents |
title | Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents |
title_full | Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents |
title_fullStr | Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents |
title_full_unstemmed | Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents |
title_short | Same-Day Desensitization in Patients Who Experience Their First Reaction to a Platin Agent at the Oncology Day Unit: A Pilot Study to Safely Include This Technique Within the Multidisciplinary Pathways for the Diagnosis & Management of Hypersensitivity to Platin Agents |
title_sort | same-day desensitization in patients who experience their first reaction to a platin agent at the oncology day unit: a pilot study to safely include this technique within the multidisciplinary pathways for the diagnosis & management of hypersensitivity to platin agents |
topic | Allergy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552947/ https://www.ncbi.nlm.nih.gov/pubmed/36238927 http://dx.doi.org/10.3389/falgy.2022.868300 |
work_keys_str_mv | AT borrascuarterojulian samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT farzaneganminanoroxana samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT torresgorrizmariacruz samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT germansanchezadrian samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT aznarraquelcervera samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT raducanisabela samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT castellocarrascosajosevicente samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT sanchezhernandezalfredo samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents AT enriqueernesto samedaydesensitizationinpatientswhoexperiencetheirfirstreactiontoaplatinagentattheoncologydayunitapilotstudytosafelyincludethistechniquewithinthemultidisciplinarypathwaysforthediagnosismanagementofhypersensitivitytoplatinagents |