Cargando…
Differential Diagnosis of Urticarial Lesions
Urticaria is a mast cell-dependent disease, characterized by the presence of wheals, angioedema, or both in the absence of systemic symptoms. It is a common disease worldwide, with an important health burden especially in chronic situations, that last more than 6 weeks. Although urticaria is usually...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552949/ https://www.ncbi.nlm.nih.gov/pubmed/36238930 http://dx.doi.org/10.3389/falgy.2022.808543 |
_version_ | 1784806360731353088 |
---|---|
author | Matos, Ana Luísa Figueiredo, Carolina Gonçalo, Margarida |
author_facet | Matos, Ana Luísa Figueiredo, Carolina Gonçalo, Margarida |
author_sort | Matos, Ana Luísa |
collection | PubMed |
description | Urticaria is a mast cell-dependent disease, characterized by the presence of wheals, angioedema, or both in the absence of systemic symptoms. It is a common disease worldwide, with an important health burden especially in chronic situations, that last more than 6 weeks. Although urticaria is usually a straightforward diagnosis, some diseases presenting with urticarial lesions must be excluded, particularly urticarial vasculitis and auto-inflammatory syndromes. In these settings additional atypical features are often present (long-lasting lesions, bruising, fever, malaise, arthralgia), allowing the clinician to suspect a diagnosis other than urticaria. The authors propose an approach based on these atypical features, the presence or absence of systemic symptoms and on skin histopathology as well as some blood parameters. |
format | Online Article Text |
id | pubmed-9552949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95529492022-10-12 Differential Diagnosis of Urticarial Lesions Matos, Ana Luísa Figueiredo, Carolina Gonçalo, Margarida Front Allergy Allergy Urticaria is a mast cell-dependent disease, characterized by the presence of wheals, angioedema, or both in the absence of systemic symptoms. It is a common disease worldwide, with an important health burden especially in chronic situations, that last more than 6 weeks. Although urticaria is usually a straightforward diagnosis, some diseases presenting with urticarial lesions must be excluded, particularly urticarial vasculitis and auto-inflammatory syndromes. In these settings additional atypical features are often present (long-lasting lesions, bruising, fever, malaise, arthralgia), allowing the clinician to suspect a diagnosis other than urticaria. The authors propose an approach based on these atypical features, the presence or absence of systemic symptoms and on skin histopathology as well as some blood parameters. Frontiers Media S.A. 2022-06-16 /pmc/articles/PMC9552949/ /pubmed/36238930 http://dx.doi.org/10.3389/falgy.2022.808543 Text en Copyright © 2022 Matos, Figueiredo and Gonçalo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Allergy Matos, Ana Luísa Figueiredo, Carolina Gonçalo, Margarida Differential Diagnosis of Urticarial Lesions |
title | Differential Diagnosis of Urticarial Lesions |
title_full | Differential Diagnosis of Urticarial Lesions |
title_fullStr | Differential Diagnosis of Urticarial Lesions |
title_full_unstemmed | Differential Diagnosis of Urticarial Lesions |
title_short | Differential Diagnosis of Urticarial Lesions |
title_sort | differential diagnosis of urticarial lesions |
topic | Allergy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552949/ https://www.ncbi.nlm.nih.gov/pubmed/36238930 http://dx.doi.org/10.3389/falgy.2022.808543 |
work_keys_str_mv | AT matosanaluisa differentialdiagnosisofurticariallesions AT figueiredocarolina differentialdiagnosisofurticariallesions AT goncalomargarida differentialdiagnosisofurticariallesions |