Acute myocardial infarction immediately after second vaccination for coronavirus disease 2019

We present a serious and rare case of acute myocardial infarction soon after the administration of second vaccination for coronavirus disease 2019. Patient's culprit lesion in the right coronary artery was identified and appropriately treated using intravascular imaging. Postvaccination monitoring of patients who are at high risk of cardiovascular diseases is critical. Rare but severe cases of acute myocardial infarction following vaccination for coronavirus disease 2019 have been reported. Physicians should consider this rare side effect as a possible differential diagnosis and appropriately manage such patients.