Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases

Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality. We present two seemingly typical cases of intraoperative MH development, with details on perioperative assessment and rescue. Postoperative ge...

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Detalles Bibliográficos
Autores principales: Chi, Xiaowei, Xu, Yi, Liao, Hongbing, Chen, Tao, Li, Qiang, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552991/
https://www.ncbi.nlm.nih.gov/pubmed/36245440
http://dx.doi.org/10.1002/ccr3.6426
Descripción
Sumario:Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality. We present two seemingly typical cases of intraoperative MH development, with details on perioperative assessment and rescue. Postoperative genetic test showed mutations in the ryanodine receptor type 1 gene.

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