Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases

Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality. We present two seemingly typical cases of intraoperative MH development, with details on perioperative assessment and rescue. Postoperative ge...

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Detalles Bibliográficos
Autores principales: Chi, Xiaowei, Xu, Yi, Liao, Hongbing, Chen, Tao, Li, Qiang, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552991/
https://www.ncbi.nlm.nih.gov/pubmed/36245440
http://dx.doi.org/10.1002/ccr3.6426
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author Chi, Xiaowei
Xu, Yi
Liao, Hongbing
Chen, Tao
Li, Qiang
Fu, Qiang
author_facet Chi, Xiaowei
Xu, Yi
Liao, Hongbing
Chen, Tao
Li, Qiang
Fu, Qiang
author_sort Chi, Xiaowei
collection PubMed
description Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality. We present two seemingly typical cases of intraoperative MH development, with details on perioperative assessment and rescue. Postoperative genetic test showed mutations in the ryanodine receptor type 1 gene.
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spelling pubmed-95529912022-10-14 Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases Chi, Xiaowei Xu, Yi Liao, Hongbing Chen, Tao Li, Qiang Fu, Qiang Clin Case Rep Case Report Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality. We present two seemingly typical cases of intraoperative MH development, with details on perioperative assessment and rescue. Postoperative genetic test showed mutations in the ryanodine receptor type 1 gene. John Wiley and Sons Inc. 2022-10-11 /pmc/articles/PMC9552991/ /pubmed/36245440 http://dx.doi.org/10.1002/ccr3.6426 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Chi, Xiaowei
Xu, Yi
Liao, Hongbing
Chen, Tao
Li, Qiang
Fu, Qiang
Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
title Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
title_full Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
title_fullStr Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
title_full_unstemmed Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
title_short Perioperative management of malignant hyperthermia during general anesthesia: A report of two cases
title_sort perioperative management of malignant hyperthermia during general anesthesia: a report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552991/
https://www.ncbi.nlm.nih.gov/pubmed/36245440
http://dx.doi.org/10.1002/ccr3.6426
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