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Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle

Uterine transplantation (UTx) is a programme of treatment aimed at providing a unique solution to absolute uterine factor infertility, enabling patients to have children as a result of their own pregnancies. As a transplant procedure performed for fertility purposes it may be thought obvious that th...

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Detalles Bibliográficos
Autor principal: O’Donovan, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552994/
https://www.ncbi.nlm.nih.gov/pubmed/36237200
http://dx.doi.org/10.1093/jlb/lsac028
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author O’Donovan, Laura
author_facet O’Donovan, Laura
author_sort O’Donovan, Laura
collection PubMed
description Uterine transplantation (UTx) is a programme of treatment aimed at providing a unique solution to absolute uterine factor infertility, enabling patients to have children as a result of their own pregnancies. As a transplant procedure performed for fertility purposes it may be thought obvious that the welfare of any children created should be assessed prior to treatment provision. However, major concerns about the breadth and scope of such requirements, and the potential threat they pose to patients' reproductive autonomy, have been raised. In this paper, I analyse novel questions regarding the role of the pre-conception welfare principle in UTx. After outlining traditional critiques of the principle, I focus on the unique issues raised by its application in the two areas of medicine occupied by UTx. As a treatment for a particular form of infertility, I explore whether law and policy regulating traditional assisted reproductive technologies applies equally to the case of UTx, and whether a distinction (in welfare terms) does and should exist between fertility treatment involving gametes and embryos and gynaecological surgery for fertility purposes. As a quality-of-life-enhancing transplant, I consider and reject proposals in favour of using pre-conception welfare considerations to inform patient listing and the allocation of deceased donor uteri on the grounds that such assessments may both compromise patient autonomy and lead to unjust discrimination against particular patients or groups of patients.
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spelling pubmed-95529942022-10-12 Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle O’Donovan, Laura J Law Biosci Original Article Uterine transplantation (UTx) is a programme of treatment aimed at providing a unique solution to absolute uterine factor infertility, enabling patients to have children as a result of their own pregnancies. As a transplant procedure performed for fertility purposes it may be thought obvious that the welfare of any children created should be assessed prior to treatment provision. However, major concerns about the breadth and scope of such requirements, and the potential threat they pose to patients' reproductive autonomy, have been raised. In this paper, I analyse novel questions regarding the role of the pre-conception welfare principle in UTx. After outlining traditional critiques of the principle, I focus on the unique issues raised by its application in the two areas of medicine occupied by UTx. As a treatment for a particular form of infertility, I explore whether law and policy regulating traditional assisted reproductive technologies applies equally to the case of UTx, and whether a distinction (in welfare terms) does and should exist between fertility treatment involving gametes and embryos and gynaecological surgery for fertility purposes. As a quality-of-life-enhancing transplant, I consider and reject proposals in favour of using pre-conception welfare considerations to inform patient listing and the allocation of deceased donor uteri on the grounds that such assessments may both compromise patient autonomy and lead to unjust discrimination against particular patients or groups of patients. Oxford University Press 2022-10-11 /pmc/articles/PMC9552994/ /pubmed/36237200 http://dx.doi.org/10.1093/jlb/lsac028 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Duke University School of Law, Harvard Law School, Oxford University Press, and Stanford Law School. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
O’Donovan, Laura
Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
title Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
title_full Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
title_fullStr Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
title_full_unstemmed Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
title_short Why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
title_sort why uterine transplantation requires us to rethink the role of the pre-conception welfare principle
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552994/
https://www.ncbi.nlm.nih.gov/pubmed/36237200
http://dx.doi.org/10.1093/jlb/lsac028
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