Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP

Fragile X-Syndrome (FXS) represents the most common inherited form of intellectual disability and the leading monogenic cause of Autism Spectrum Disorders. In most cases, this disease results from the absence of expression of the protein FMRP encoded by the FMR1 gene (Fragile X messenger ribonucleop...

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Detalles Bibliográficos
Autores principales: Kieffer, Félicie, Hilal, Fahd, Gay, Anne-Sophie, Debayle, Delphine, Pronot, Marie, Poupon, Gwénola, Lacagne, Iliona, Bardoni, Barbara, Martin, Stéphane, Gwizdek, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553004/
https://www.ncbi.nlm.nih.gov/pubmed/36237573
http://dx.doi.org/10.3389/fmolb.2022.954087

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