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Kidney Angiotensin in Cardiovascular Disease: Formation and Drug Targeting

The concept of local formation of angiotensin II in the kidney has changed over the last 10–15 years. Local synthesis of angiotensinogen in the proximal tubule has been proposed, combined with prorenin synthesis in the collecting duct. Binding of prorenin via the so-called (pro)renin receptor has be...

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Detalles Bibliográficos
Autores principales: Lin, Hui, Geurts, Frank, Hassler, Luise, Batlle, Daniel, Mirabito Colafella, Katrina M., Denton, Kate M., Zhuo, Jia L., Li, Xiao C., Ramkumar, Nirupama, Koizumi, Masahiro, Matsusaka, Taiji, Nishiyama, Akira, Hoogduijn, Martin J., Hoorn, Ewout J., Danser, A.H. Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553117/
https://www.ncbi.nlm.nih.gov/pubmed/35710133
http://dx.doi.org/10.1124/pharmrev.120.000236

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