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Kidney Angiotensin in Cardiovascular Disease: Formation and Drug Targeting
The concept of local formation of angiotensin II in the kidney has changed over the last 10–15 years. Local synthesis of angiotensinogen in the proximal tubule has been proposed, combined with prorenin synthesis in the collecting duct. Binding of prorenin via the so-called (pro)renin receptor has be...
Autores principales: | Lin, Hui, Geurts, Frank, Hassler, Luise, Batlle, Daniel, Mirabito Colafella, Katrina M., Denton, Kate M., Zhuo, Jia L., Li, Xiao C., Ramkumar, Nirupama, Koizumi, Masahiro, Matsusaka, Taiji, Nishiyama, Akira, Hoogduijn, Martin J., Hoorn, Ewout J., Danser, A.H. Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553117/ https://www.ncbi.nlm.nih.gov/pubmed/35710133 http://dx.doi.org/10.1124/pharmrev.120.000236 |
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