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Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury

BACKGROUND: Oxidative damage is critical in the pathogenesis of ovarian ischaemia/reperfusion (I/R) injury, and statins have been reported to exert antioxidant activity. However, the role of VCAM-1 and xanthine oxidase (XO)/uric acid (UA) in ovarian I/R injury is not known. Also, whether or not ator...

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Detalles Bibliográficos
Autores principales:	Afolabi, O. A., Hamed, M. A., Anyogu, D. C., Adeyemi, D. H., Odetayo, A. F., Akhigbe, R. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553180/ https://www.ncbi.nlm.nih.gov/pubmed/36200598 http://dx.doi.org/10.1080/13510002.2022.2129192

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