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A single cell transcriptional roadmap of human pacemaker cell differentiation

Each heartbeat is triggered by the sinoatrial node (SAN), the primary pacemaker of the heart. Studies in animal models have revealed that pacemaker cells share a common progenitor with the (pro)epicardium, and that the pacemaker cardiomyocytes further diversify into ‘transitional’, ‘tail’, and ‘head...

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Detalles Bibliográficos
Autores principales: Wiesinger, Alexandra, Li, Jiuru, Fokkert, Lianne, Bakker, Priscilla, Verkerk, Arie O, Christoffels, Vincent M, Boink, Gerard JJ, Devalla, Harsha D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553210/
https://www.ncbi.nlm.nih.gov/pubmed/36217819
http://dx.doi.org/10.7554/eLife.76781