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Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

While the lung bears significant regenerative capacity, severe viral pneumonia can chronically impair lung function by triggering dysplastic remodeling. The connection between these enduring changes and chronic disease remains poorly understood. We recently described the emergence of tuft cells with...

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Detalles Bibliográficos
Autores principales: Barr, Justinn, Gentile, Maria Elena, Lee, Sunyoung, Kotas, Maya E, Fernanda de Mello Costa, Maria, Holcomb, Nicolas P, Jaquish, Abigail, Palashikar, Gargi, Soewignjo, Marcella, McDaniel, Margaret, Matsumoto, Ichiro, Margolskee, Robert, Von Moltke, Jakob, Cohen, Noam A, Sun, Xin, Vaughan, Andrew E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553214/
https://www.ncbi.nlm.nih.gov/pubmed/36073526
http://dx.doi.org/10.7554/eLife.78074