Cargando…
PRL/PRLR Can Promote Insulin Resistance by Activating the JAK2/STAT5 Signaling Pathway
OBJECTIVE: Although prolactin (PRL) is known to affect food intake, weight gain, and insulin resistance, its effects on lipid metabolism and underlying mechanisms remain underinvestigated. This study aimed to investigate the effects of PRL and its receptor (PRLR) on fat metabolism in regulating the...
Autores principales: | Wang, Pei-yu, Jin, Cong-cong, Liu, Chang, Zhao, Zhou-jian, Yang, Hai-yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553348/ https://www.ncbi.nlm.nih.gov/pubmed/36238467 http://dx.doi.org/10.1155/2022/1456187 |
Ejemplares similares
-
PRLR Regulates Hepatic Insulin Sensitivity in Mice via STAT5
por: Yu, Junjie, et al.
Publicado: (2013) -
Bu-Shen-Zhu-Yun decoction induces PRLR deubiquitination and JAK2/STAT5 activation via CSN5 in vitro
por: Feng, Hua, et al.
Publicado: (2021) -
Energy deprivation-induced AMPK activation inhibits milk synthesis by targeting PrlR and PGC-1α
por: Wu, Zhihui, et al.
Publicado: (2022) -
A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the Multiethnic Cohort
por: Lee, Sulggi A, et al.
Publicado: (2007) -
Targeting Prolactin Receptor (PRLR) Signaling in PRLR-Positive Breast and Prostate Cancer
por: O’Sullivan, Ciara C., et al.
Publicado: (2016)