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Elacestrant (oral selective estrogen receptor degrader) Versus Standard Endocrine Therapy for Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: Results From the Randomized Phase III EMERALD Trial
Patients with pretreated estrogen receptor (ER)–positive/human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer have poor prognosis. Elacestrant is a novel, oral selective ER degrader that demonstrated activity in early studies. METHODS: This randomized, open-label, phase II...
Autores principales: | Bidard, Francois-Clement, Kaklamani, Virginia G., Neven, Patrick, Streich, Guillermo, Montero, Alberto J., Forget, Frédéric, Mouret-Reynier, Marie-Ange, Sohn, Joo Hyuk, Taylor, Donatienne, Harnden, Kathleen K., Khong, Hung, Kocsis, Judit, Dalenc, Florence, Dillon, Patrick M., Babu, Sunil, Waters, Simon, Deleu, Ines, García Sáenz, José A., Bria, Emilio, Cazzaniga, Marina, Lu, Janice, Aftimos, Philippe, Cortés, Javier, Liu, Shubin, Tonini, Giulia, Laurent, Dirk, Habboubi, Nassir, Conlan, Maureen G., Bardia, Aditya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553388/ https://www.ncbi.nlm.nih.gov/pubmed/35584336 http://dx.doi.org/10.1200/JCO.22.00338 |
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