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Survivin Splice Variant 2β Enhances Pancreatic Ductal Adenocarcinoma Resistance to Gemcitabine

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with poor prognosis, as it is difficult to predict or circumvent, and it develops chemoresistance quickly. One cellular mechanism associated with chemoresistance is alternative splicing dysfunction, a process through whic...

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Detalles Bibliográficos
Autores principales:	Fuller, Ryan N, Kabagwira, Janviere, Vallejos, Paul A, Folkerts, Andrew D, Wall, Nathan R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553431/ https://www.ncbi.nlm.nih.gov/pubmed/36238134 http://dx.doi.org/10.2147/OTT.S341720

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