Downregulation of Matriptase Inhibits Porphyromonas gingivalis Lipopolysaccharide-Induced Matrix Metalloproteinase-1 and Proinflammatory Cytokines by Suppressing the TLR4/NF-κB Signaling Pathways in Human Gingival Fibroblasts

Matriptases are cell surface proteolytic enzymes belonging to the type II transmembrane serine protease family that mediate inflammatory skin disorders and cancer progression. Matriptases may affect the development of periodontitis via protease-activated receptor-2 activity. However, the cellular me...

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Detalles Bibliográficos
Autores principales: Kim, Jeong-Mi, Noh, Eun-Mi, You, Yong-Ouk, Kim, Min Seuk, Lee, Young-Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553488/
https://www.ncbi.nlm.nih.gov/pubmed/36246974
http://dx.doi.org/10.1155/2022/3865844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553488/
https://www.ncbi.nlm.nih.gov/pubmed/36246974
http://dx.doi.org/10.1155/2022/3865844

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