Cargando…

Correlation Study on the Expression of INSR, IRS-1, and PD-L1 in Nonsmall Cell Lung Cancer

OBJECTIVE: To study the expression and correlation of insulin receptor (INSR), insulin receptor substrate-1 (IRS-1), and programmed cell death ligand-1 (PD-L1) in nonsmall cell lung cancer (NSCLC). METHODS: 45 lung cancer tissues and 30 adjacent normal tissues of NSCLC patients diagnosed in the Seco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ting, Ma, Miao, Yu-e, Yu, Feng-xiu, Luo, Guang-cai, Xu, Xin, Xiao, Li-xia, Zhang, Guo-qing, Chang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553505/ https://www.ncbi.nlm.nih.gov/pubmed/36245982 http://dx.doi.org/10.1155/2022/5233222

Ejemplares similares

INSR novel mutations identified in a Chinese family with severe INSR-related insulin resistance syndromes: A case report
por: Yu, Lu, et al.
Publicado: (2022)

A meta-analysis of efficacy and safety of antibodies targeting PD-1/PD-L1 in treatment of advanced nonsmall cell lung cancer
por: Wang, Cuihua, et al.
Publicado: (2016)

Molecular Mechanism of Expression Changes of Immunological Indexes of PD-1/sPD-L1 after Radiotherapy in Nonsmall Cell Lung Cancer
por: Qu, Yanli, et al.
Publicado: (2021)

The correlation of serum sPD-1 and sPD-L1 levels with clinical, pathological characteristics and lymph node metastasis in nonsmall cell lung cancer patients
por: ANCIN, Burcu, et al.
Publicado: (2022)

Anti-PD-1/PD-L1 antibody therapy for pretreated advanced nonsmall-cell lung cancer: A meta-analysis of randomized clinical trials
por: Zhou, Guo-Wu, et al.
Publicado: (2016)

High sensitivity of PD-L1 analysis from pleural effusion in nonsmall cell lung cancer
por: Hagmeyer, Lars, et al.
Publicado: (2021)

Reducing IRS-1 Activation Cause Mutation of Tyrosine Kinase Domain hINSR Gene on Type-2 Diabetes Mellitus Patients
por: Fatchiyah, Fatchiyah, et al.
Publicado: (2013)

Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1
por: Yang, Won-Mo, et al.
Publicado: (2016)

Anti-PD-1/PD-L1 Antibody Therapy for Pretreated Advanced or Metastatic Nonsmall Cell Lung Carcinomas and the Correlation between PD-L1 Expression and Treatment Effectiveness: An Update Meta-Analysis of Randomized Clinical Trials
por: Zhao, Qiuling, et al.
Publicado: (2018)

Immune-related adverse events associated with PD-1 and PD-L1 inhibitors for nonsmall cell lung cancer: Protocol for a systematic review and meta-analysis
por: Sun, Xiaoying, et al.
Publicado: (2017)

The association of efficacy with PD-1/PD-L1 inhibition and tumor mutational burden in advanced nonsmall cell lung cancer: A PRISMA-guided literature review and meta-analysis
por: Yu, Dahui, et al.
Publicado: (2022)

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter
por: Sarfstein, Rive, et al.
Publicado: (2020)

PD‐0332991 combined with cisplatin inhibits nonsmall cell lung cancer and reversal of cisplatin resistance
por: Liu, Minghui, et al.
Publicado: (2021)

The Role of INSR & Diabetes in Polycystic Ovarian Syndrome
por: KHAZAMIPOUR, Afrouz, et al.
Publicado: (2018)

Transcriptional Regulation of INSR, the Insulin Receptor Gene
por: Payankaulam, Sandhya, et al.
Publicado: (2019)

Comparison of programmed death-ligand 1 (PD-L1) immunostain for nonsmall cell lung carcinoma between paired cytological and surgical specimens
por: Xu, Huihong, et al.
Publicado: (2018)

Combinatorial assessment of ctDNA release and mutational burden predicts anti‐PD(L)1 therapy outcome in nonsmall‐cell lung cancer
por: Fang, Wenfeng, et al.
Publicado: (2020)

InsR/FoxO1 Signaling Curtails Hypothalamic POMC Neuron Number
por: Plum, Leona, et al.
Publicado: (2012)

INSR and ISR‑1 gene polymorphisms and the susceptibility of essential hypertension: A meta‑analysis
por: Wang, Yan, et al.
Publicado: (2023)

PD-L1 and PD-1 expression correlate with prognosis in extrahepatic cholangiocarcinoma
por: Ma, Ke, et al.
Publicado: (2017)

The Potential Mechanism of HDAC1-Catalyzed Histone Crotonylation of Caspase-1 in Nonsmall Cell Lung Cancer
por: Jiang, Chuan, et al.
Publicado: (2022)

Insulin Receptor and the Kidney: Nephrocalcinosis in Patients with Recessive INSR Mutations
por: Simpkin, Arabella, et al.
Publicado: (2014)

RS1799817 in INSR associates with susceptibility to polycystic ovary syndrome
por: Daghestani, Maha H.
Publicado: (2020)

CircINSR Regulates Fetal Bovine Muscle and Fat Development
por: Shen, Xuemei, et al.
Publicado: (2021)

Expressions of KAI1 and E-cadherin in nonsmall cell lung cancer and their correlation with vasculogenic mimicry
por: Ci, Hongfei, et al.
Publicado: (2018)

Igf1R/InsR function is required for axon extension and corpus callosum formation
por: Jin, Jing, et al.
Publicado: (2019)

The Association between Polymorphism of INSR and Polycystic Ovary Syndrome: A Meta-Analysis
por: Feng, Chun, et al.
Publicado: (2015)

The Role of Neurotrophin-4/Forkhead Box L1 in the Development of Nonsmall-Cell Lung Cancer
por: Mu, Lin, et al.
Publicado: (2022)

Modulating paired Ir–O–Ir via electronic perturbations of correlated Ir single atoms to overcome catalytic selectivity
por: Chen, Shi-Hua, et al.
Publicado: (2023)

Fibroblast Growth Factor Receptor 1 Gene Amplification in Nonsmall Cell Lung Cancer
por: Miao, Jian-Long, et al.
Publicado: (2016)

Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer
por: Qing, Yi, et al.
Publicado: (2015)

Insulin–InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages
por: Xia, Pengyan, et al.
Publicado: (2015)

Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo
por: Ofer, Philipp, et al.
Publicado: (2015)

MicroRNA 322 Aggravates Dexamethasone-Induced Muscle Atrophy by Targeting IGF1R and INSR
por: Geng, Hongwei, et al.
Publicado: (2020)

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline
por: Kian, Mahdie, et al.
Publicado: (2022)

A Mutation in INSR in a Child Presenting with Severe Acanthosis Nigricans
por: Tuhan, Hale, et al.
Publicado: (2017)

CMTM6, the newly identified PD-L1 regulator, correlates with PD-L1 expression in lung cancers
por: Gao, Feng, et al.
Publicado: (2019)

Insulin glargine affects the expression of Igf-1r, Insr, and Igf-1 genes in colon and liver of diabetic rats
por: Juárez-Vázquez, Clara I, et al.
Publicado: (2018)

Expression of PD-1/PD-L1 in peripheral blood and tumor tissues of patients with classical Hodgkin’s lymphoma
por: Feng, Xia, et al.
Publicado: (2023)

PD-1 and PD-L1 expression in 132 recurrent nasopharyngeal carcinoma: the correlation with anemia and outcomes
por: Zhou, Yajuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i0m9lc0ker3qf2qcfs2p3ijivo