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The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade
The secondary metabolites isolated from soil fungi have received more and more attention, especially new compounds that exhibited good biological activities. In this review, a total of 546 new compounds are included in the relevant literature since 2011. The new compounds are isolated from soil fung...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553542/ https://www.ncbi.nlm.nih.gov/pubmed/36248243 http://dx.doi.org/10.2147/DDDT.S377921 |
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author | Zhang, Danyu Li, Shoujie Fan, Mohan Zhao, Changqi |
author_facet | Zhang, Danyu Li, Shoujie Fan, Mohan Zhao, Changqi |
author_sort | Zhang, Danyu |
collection | PubMed |
description | The secondary metabolites isolated from soil fungi have received more and more attention, especially new compounds that exhibited good biological activities. In this review, a total of 546 new compounds are included in the relevant literature since 2011. The new compounds are isolated from soil fungi, We divided these compounds into seven categories, including alkaloids, terpenoids, steroids, ketones, phenylpropanoids, quinones, esters, lactones, etc. In addition, the biological activities and structure–activity relationships of these compounds have also been fully discussed. The activities of these compounds are roughly divided into eight categories, including anticancer activity, antimicrobial activity, anti-inflammatory activity, antioxidant activity, antiviral activity, antimalarial activity, immunosuppressive activity and other activities. Since natural products are an important source of new drugs, this review may have a positive guiding effect on drug screening. |
format | Online Article Text |
id | pubmed-9553542 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-95535422022-10-13 The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade Zhang, Danyu Li, Shoujie Fan, Mohan Zhao, Changqi Drug Des Devel Ther Review The secondary metabolites isolated from soil fungi have received more and more attention, especially new compounds that exhibited good biological activities. In this review, a total of 546 new compounds are included in the relevant literature since 2011. The new compounds are isolated from soil fungi, We divided these compounds into seven categories, including alkaloids, terpenoids, steroids, ketones, phenylpropanoids, quinones, esters, lactones, etc. In addition, the biological activities and structure–activity relationships of these compounds have also been fully discussed. The activities of these compounds are roughly divided into eight categories, including anticancer activity, antimicrobial activity, anti-inflammatory activity, antioxidant activity, antiviral activity, antimalarial activity, immunosuppressive activity and other activities. Since natural products are an important source of new drugs, this review may have a positive guiding effect on drug screening. Dove 2022-10-12 /pmc/articles/PMC9553542/ /pubmed/36248243 http://dx.doi.org/10.2147/DDDT.S377921 Text en © 2022 Zhang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Zhang, Danyu Li, Shoujie Fan, Mohan Zhao, Changqi The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade |
title | The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade |
title_full | The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade |
title_fullStr | The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade |
title_full_unstemmed | The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade |
title_short | The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade |
title_sort | novel compounds with biological activity derived from soil fungi in the past decade |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553542/ https://www.ncbi.nlm.nih.gov/pubmed/36248243 http://dx.doi.org/10.2147/DDDT.S377921 |
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