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Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading to alveolar destruction in the lungs. Mitotic...

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Detalles Bibliográficos
Autores principales:	Wang, Lan, Wan, Ruyan, Chen, Xinyu, Guo, Xiaoshu, Li, Zhongzheng, Zhao, Weiming, Yan, Peishuo, Yu, Guoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553670/ https://www.ncbi.nlm.nih.gov/pubmed/36247080 http://dx.doi.org/10.1155/2022/9663354

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