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Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model

BACKGROUND AND AIMS: The nacht domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is upregulated in human abdominal aortic aneurysm (AAA), but its pathogenic role is unclear. The aims of this study were firstly to examine whether the inflammasome was upregulated...

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Detalles Bibliográficos
Autores principales: Phie, James, Thanigaimani, Shivshankar, Huynh, Pacific, Anbalagan, Raghuveeran, Moran, Corey S., Kinobe, Robert, Moxon, Joseph V., Field, Matt A., Krishna, Smriti M., Golledge, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553691/
https://www.ncbi.nlm.nih.gov/pubmed/36262119
http://dx.doi.org/10.1155/2022/5299370