Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank

BACKGROUND: Prostate cancer is highly heritable, with >250 common variants associated in genome-wide association studies. It commonly presents with non-specific lower urinary tract symptoms that are frequently associated with benign conditions. METHODS: Cohort study using UK Biobank data linked t...

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Detalles Bibliográficos
Autores principales: Green, Harry D., Merriel, Samuel W. D., Oram, Richard A., Ruth, Katherine S., Tyrrell, Jessica, Jones, Samuel E., Thirlwell, Chrissie, Weedon, Michael N., Bailey, Sarah E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553867/
https://www.ncbi.nlm.nih.gov/pubmed/35978138
http://dx.doi.org/10.1038/s41416-022-01918-z

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