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Integrative multiomic analyses of dorsal root ganglia in diabetic neuropathic pain using proteomics, phospho-proteomics, and metabolomics

Diabetic peripheral neuropathy (DPN) is characterized by spontaneous pain in the extremities. Incidence of DPN continues to rise with the global diabetes epidemic. However, there remains a lack of safe, effective analgesics to control this chronic painful condition. Dorsal root ganglia (DRG) contain...

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Detalles Bibliográficos
Autores principales: Doty, Megan, Yun, Sijung, Wang, Yan, Hu, Minghan, Cassidy, Margaret, Hall, Bradford, Kulkarni, Ashok B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553906/
https://www.ncbi.nlm.nih.gov/pubmed/36220867
http://dx.doi.org/10.1038/s41598-022-21394-y