Cargando…
Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine
Post-transcriptional RNA editing modulates gene expression in a condition-dependent fashion. We recently discovered C-to-Ψ editing in Vibrio cholerae tRNA. Here, we characterize the biogenesis, regulation, and functions of this previously undescribed RNA editing process. We show that an enzyme, TrcP...
Autores principales: | Kimura, Satoshi, Srisuknimit, Veerasak, McCarty, Kacie L., Dedon, Peter C., Kranzusch, Philip J., Waldor, Matthew K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553926/ https://www.ncbi.nlm.nih.gov/pubmed/36220828 http://dx.doi.org/10.1038/s41467-022-33714-x |
Ejemplares similares
-
Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host–pathogen conflict
por: Eaglesham, James B, et al.
Publicado: (2020) -
Formation of the conserved pseudouridine at position 55 in archaeal tRNA
por: Roovers, Martine, et al.
Publicado: (2006) -
Undecaprenyl phosphate translocases confer conditional microbial fitness
por: Sit, Brandon, et al.
Publicado: (2022) -
tRNA elbow modifications affect the tRNA pseudouridine synthase TruB and the methyltransferase TrmA
por: Schultz, Sarah Kai-Leigh, et al.
Publicado: (2020) -
Pseudouridine-mediated translation control of mRNA by methionine aminoacyl tRNA synthetase
por: Levi, Ofri, et al.
Publicado: (2020)